<p>Shiru leverages computational design to create enhanced proteins that feed the world sustainably.</p>

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"Computational design of proteins for a sustainable food future"

<div><b style="font-size:12pt;">About Us</b></div><div><span style="font-size:12pt;">At Shiru, we believe that the most powerful solutions to global challenges are found in nature—and that AI-driven discovery can unlock them faster than ever before. Our mission is to create high-quality, functional proteins that drive sustainability, performance, and efficiency across multiple industries—from food and agriculture to materials and beyond.</span></div><div><br></div><div><span style="font-size:12pt;">By applying computational intelligence, we identify highly functional, natural proteins and harness the inherent capabilities of biological systems to produce them at scale. From next-generation food ingredients to bio-based materials, biopesticides, and more, Shiru is pioneering a new era of sustainable innovation</span><a style="font-size:12pt;" href="http://innovation.we/">.</a></div><div><br></div><div><span style="font-size:12pt;">We partner with industry-leading companies to bring these discoveries to market, ensuring that our innovations don’t just stay in the lab—they create real-world impact. As we continue to grow, we’re building a team of passionate, cross-disciplinary professionals committed to transforming industries and shaping a more sustainable future.</span></div><div><br></div><div><b style="font-size:12pt;">About the Role</b></div><div><span style="font-size:12pt;">We are looking for an enthusiastic and detail-oriented Research Associate to join our Protein Chemistry team. You will work closely with Shiru’s scientists to execute and improve our protein production and purification workflows. As a key member of an early stage multi-disciplinary team, you will have ample opportunities to learn cutting-edge science in a collaborative environment, hone your laboratory and scientific decision-making skills, and contribute to our collective mission with ever-increasing autonomy. </span></div><div><br></div><div><b style="font-size:12pt;">About You:</b><span style="font-size:12pt;"> You are an enthusiastic and hyper-organized self-starter. You keep a list of your lists, and checking items off of them gives you a great sense of satisfaction. You find yourself “in the flow” when you are working with your hands and at the bench. Your curiosity and attention to detail help you spot problems, ask questions, and identify solutions. Your positive mindset and collaborative attitude make you a great team player. You have excellent interpersonal and time-management skills, and a passion for science, food, and sustainability.</span></div><div><br></div><div><b style="font-size:16px;">This is a six-month fixed-term position with the possibility of extension based on business needs, performance, and other factors. </b></div><br><br><h3>Responsibilities</h3><ul><li>Conduct protein production and purification experiments, including cell lysis, filtration, and chromatography</li><li>Collect, analyze, and summarize analytical data to characterize protein sample properties such as purity, stability, and size</li><li>Initiate fermentation runs, from seed culture to shake flask, as necessary to feed protein production pipelines</li><li>Troubleshoot existing purification equipment and/or protocols</li><li>Maintain a detailed record of results using an Electronic Laboratory Notebook, enabling efficient data capture, analysis, and communication</li><li>Contribute to a safe working environment through equipment maintenance and chemical handling</li></ul><h3>Attributes</h3><ul><li>You enjoy working on scientific problems and applying your analytical and problem-solving skills</li><li>You bring a positive attitude to individual and collaborative projects</li><li>Good organizational habits and time-management skills</li><li>Ability to work independently and troubleshoot resourcefully; you’re not afraid to make or discuss mistakes and you’re keen to continuously improve your skills and the quality of your work</li><li>Excellent communication skills and a demonstrated ability to thrive in a dynamic, fast-paced environment</li></ul><h3>Requirements</h3><ul><li>A.S./B.S. degree in biochemistry, molecular biology, microbiology, bioengineering, chemical engineering, or a related discipline; with 1+ yrs industrial experience</li><li>Experience with standard bench scale purification techniques, such as centrifugation, FPLC, and cell lysis</li><li>Experience with core protein analytical methods, including SDS-PAGE, ELISA, and colorimetric assays like BCA or Pierce660</li><li>Familiarity with molecular biology techniques, including PCR or microbial transformation, is a plus</li><li>Familiarity with SQL and/or Python a plus</li><div><br></div></ul><br><div>We encourage you to apply even if you don’t meet every single requirement. Studies show that individuals from historically underrepresented groups, including women, are less likely to apply unless they meet all qualifications. We value diverse experiences and perspectives, and we believe skills can be transferable. If this role excites you, we’d love to hear from you!</div>

Research Associate - Protein Chemistry

<div><b style="font-size:12pt;">About Us</b></div><div><span style="font-size:12pt;">At Shiru, we believe that the most powerful solutions to global challenges are found in nature—and that AI-driven discovery can unlock them faster than ever before. Our mission is to create high-quality, functional proteins that drive sustainability, performance, and efficiency across multiple industries—from food and agriculture to materials and beyond.</span></div><div><br></div><div><span style="font-size:12pt;">By applying computational intelligence, we identify highly functional, natural proteins and harness the inherent capabilities of biological systems to produce them at scale. From next-generation food ingredients to bio-based materials, biopesticides, and more, Shiru is pioneering a new era of sustainable innovation</span><a style="font-size:12pt;" href="http://innovation.We">.</a></div><div><br></div><div><span style="font-size:12pt;">We partner with industry-leading companies to bring these discoveries to market, ensuring that our innovations don’t just stay in the lab—they create real-world impact. As we continue to grow, we’re building a team of passionate, cross-disciplinary professionals committed to transforming industries and shaping a more sustainable future.</span></div><div><br></div><div><b style="font-size:12pt;">About the Role</b></div><div><span style="font-size:12pt;">We are looking for an enthusiastic and detail-oriented Research Associate to join our Molecular Biology team. You will work closely with Shiru’s scientists to design, execute, and improve our strain engineering workflows to express a diverse range of functional proteins. As a key member of an early stage multi-disciplinary team, you will have ample opportunities to learn cutting-edge science in a collaborative environment, hone your laboratory and scientific decision-making skills, and contribute to our collective mission with ever-increasing autonomy. </span></div><div><br></div><div><b style="font-size:12pt;">About You:</b><span style="font-size:12pt;"> You are an enthusiastic and hyper-organized self-starter. You keep a list of your lists, and checking items off of them gives you a great sense of satisfaction. You find yourself “in the flow” when you are working with your hands and at the bench. Your curiosity and attention to detail help you spot problems, ask questions, and identify solutions. Your positive mindset and collaborative attitude make you a great team player. You have excellent interpersonal and time-management skills, and a passion for science, food, and sustainability.</span></div><div><br></div><div><b style="font-size:16px;">This is a six-month fixed-term position with the possibility of extension based on business needs, performance, and other factors. </b></div><div><br></div><br><br><h3>Responsibilities</h3><ul><li>Routinely design and construct DNA expression cassettes for use in E. coli or yeast hosts</li><li>Design, build and test microbial strains that produce diverse functional proteins</li><li>Collect, analyze, and summarize data in the form of short reports and brief presentations</li><li>Troubleshoot existing molecular biology protocols and support the development of new processes</li><li>Maintain a detailed record of results using an Electronic Laboratory Notebook, enabling efficient data capture, analysis, and communication</li><li>Contribute to a safe working environment through equipment maintenance and chemical handling</li></ul><h3>Attributes</h3><ul><li>You enjoy working on scientific problems and applying your analytical and problem-solving skills</li><li>You bring a positive attitude to individual and collaborative projects</li><li>Good organizational habits and time-management skills</li><li>Ability to work independently and troubleshoot resourcefully; you’re not afraid to make or discuss mistakes and you’re keen to continuously improve your skills and the quality of your work</li><li>Excellent communication skills and a demonstrated ability to thrive in a dynamic, fast-paced environment</li></ul><h3>Requirements</h3><ul><li>A.S./B.S. degree in molecular biology, biochemistry, genetics, microbiology, chemical engineering, or a related discipline; with 1+ yrs industrial experience</li><li>Experience with molecular biology techniques, including PCR, plasmid/DNA design, DNA sequence analysis, microbial transformation,  microbial culture and aseptic technique</li><li>Experience in protein expression engineering, synthetic biology and genome editing preferred but not required</li><li>Familiarity with purification techniques like cell lysis and chromatography a plus</li><li>Familiarity with SQL and/or Python a plus</li></ul><br><div>We encourage you to apply even if you don’t meet every single requirement. Studies show that individuals from historically underrepresented groups, including women, are less likely to apply unless they meet all qualifications. We value diverse experiences and perspectives, and we believe skills can be transferable. If this role excites you, we’d love to hear from you!</div>

Research Associate - Molecular Biology

<div><span style="font-size:32px;">About us </span></div><div><span style="font-size:11pt;">At Shiru we believe that food should be delicious and nourishing without negatively affecting our planet. Acknowledging our growing global population as well as the imminent effects of climate change, Shiru’s mission is to create better protein ingredients that will catapult us into a sustainable food future. </span></div><div><br></div><div><span style="font-size:11pt;">With our mission in mind, Shiru makes high quality, functional food proteins through better leveraging our precious environmental resources. To do this, we employ technologies originally  created to solve problems in adjacent industries, including computational biology, machine learning, and industrial fermentation and bioprocessing.</span></div><div><br></div><div><span style="font-size:11pt;">We apply computational intelligence to find the most functional natural food proteins in the world, harnessing the inherent ability of microflora to produce them. We then partner with food and beverage companies to incorporate these unique protein ingredients into everyday products. Shiru is now expanding our team of dedicated professionals across multiple disciplines to make enhanced protein ingredients for a better world.</span></div><div><br></div><div><span style="font-size:32px;">Our ask </span></div><div><br></div><div>Don’t see a specific job that matches your qualifications? While all of our active openings are listed, feel free to apply here and detail the type of job you are looking for.</div><div> </div><div>Please include your resume and a cover letter that explains why your skillset and experience would be an asset to Shiru - we'll be opening several new roles soon and searching for great talent.</div><br><br><br><div><span style="font-size:11pt;">At Shiru, we're looking for people with passion, grit, and integrity. You're encouraged to apply even if your experience doesn't precisely match the job description. We’re expecting your skills and passion to stand out—and set you apart—especially if your career has taken some extraordinary twists and turns. Please join us in this singular opportunity to create the future of food!  </span></div><div><br></div><div>Shiru is an equal opportunity employer who values diversity. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Shiru offers competitive compensation and employee benefits along with an attractive equity package commensurate with candidate qualifications.</div>

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