Joyn Bio is a joint venture between Bayer and Ginkgo BioWorks dedicated to addressing unmet needs in agriculture by applying synthetic biology approaches to engineer microbes.
Objective
Serve as a key senior scientific member of the Digital Sciences and Technology department. The Computational Biology Group Lead will lead, grow, and develop a team of computational biologists within Joyn who support programs that leverage synthetic biology.
Responsibilities
Guide and mentor junior/senior computational scientists, and in general act as an expert scientific leader to support and nurture collaborations with internal and external partners.
Create an innovative & collaborative computational biology strategic roadmap that directly supports strain engineering design efforts in the building of novel microbials.
Contribute to the culture of technical excellence in the following areas: microbial based multi-omics data integration via genome-scale modeling or machine learning methodologies, biomarker discovery, proteomics, metabolomics, transcriptomics, metabolite flux analysis and other whole-cell experimental techniques.
Promote transparency and intra department exchange of data and workflows, collaborating with Data Science Lead to leverage data in unique ways to create novel discoveries for programs.
Scale and productionize bioinformatics pipelines by collaborating with Scientific Computing to ensure a unified technical data platform
Ensure sufficient documentation for your solutions. Work closely with the Scientific Computing team to ensure a unified technical data platform and to support their efforts in building out the Joyn data infrastructure.
Serve as an integral member in a cross-disciplinary team, representing the research arm of Digital Sciences and Technology.
Training/Experience
PhD in Microbial Systems Science/Biology, Biological Engineering, Bioinformatics, Genomics, Data Science or a related field with 10+ years of experience in industry.
Extensive experience in building production-grade NGS pipelines with specific experience in multi-omics data integration, pathway analysis, and variant annotation.
Experience in microbial research including a working understanding of computational approaches for genomics, predictive biomarker discovery and mining/analysis of genomics databases.
Proficiency in Python, version control, containerization, workflow management solutions, and developing bioinformatics pipelines in a cloud-based environment (AWS).
Experience interfacing via APIs with multiple database types, including SQL and NoSQL.
Firm grasp of modern statistical methods and their application to high dimensional datasets.
Strong team player, who can proactively partner across teams to identify and solve organizational problems.
Ability to clearly communicate methods and findings to colleagues with varying levels of technical expertise.
A passion for creating transformative agricultural products, discovering new ways to add value to farmers.
Organizational
This position will report to the Head of the Digital Science & Technologies (DST) Dept.