We are seeking a motivated and detail-oriented Research Associate to join our interdisciplinary team at the intersection of stem cell biology and genome engineering. This role offers the opportunity to work closely with scientists developing cutting-edge approaches to drive novel applications in the modification of phenotypes across a variety of avian species. The ideal candidate will bring strong technical skills in molecular biology, excellent problem-solving abilities, and a collaborative mindset to help drive innovation in species de-extinction and conservation.Duties and Responsibilities<ul><li>Collaborate with stem cell biologists to analyze gene expression profiles across different developmental stages and sample types using RT-qPCR.</li><li>Perform molecular cloning, construct design, and troubleshooting to support the genome engineering team.</li><li>Prepare and process samples for amplicon-based next-generation sequencing.</li><li>Analyze and interpret experimental data, providing recommendations to guide project direction.</li><li>Participate in lab meetings, generate reports, and present findings to ensure alignment with project milestones.</li><li>Maintain accurate, detailed laboratory records and demonstrate strong organizational skills.</li></ul>Required Skills and Abilities<ul><li>Bachelor’s degree (B.S./B.A.) in molecular biology, or a related life science field with 1 or more years of hands-on research experience in industry or academic research labs.</li><li>High proficiency in RNA extraction, reverse transcription, qPCR. </li><li>Skilled in PCR primer design and PCR optimization/troubleshooting.</li><li>Hands-on experience in molecular cloning, plasmid construction, and plasmid preparation (mini-, midi-, and maxi-prep).</li><li>Strong organizational skills with the ability to manage multiple projects simultaneously and meet deadlines.</li><li>Excellent written and oral communication skills, with demonstrated problem-solving abilities.</li></ul>Preferred Skills and Abilities<ul><li>Experience with genome-editing technologies (e.g., CRISPR/Cas9, HDR strategies).</li><li>Experience with multiplex RT-qPCR</li><li>Familiarity with high-throughput automation platforms for molecular biology workflows.</li></ul><div>What Colossal Offers You:<ul><li style="font-weight:400;">Medical, dental, and vision coverage</li><li style="font-weight:400;">Unlimited PTO and company holidays so you can rest and recharge </li><li style="font-weight:400;">Flexible spending accounts (FSA)</li><li style="font-weight:400;">Company matched 401k retirement plan</li><li style="font-weight:400;">Paid parental leave up to 12 weeks</li><li style="font-weight:400;">Education reimbursement </li><li style="font-weight:400;">An opportunity to help us return the Earth to a healthier state</li></ul>The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices. Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive. <a href="https://www.eeoc.gov/after-june-27-2023-know-your-rights-workplace-discrimination-illegal">EEO is the Law </a>Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house. Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:<ul><li>#1 on the 50 Best Startups to Work For in Dallas in 2023!</li><li>100 Best Midsize Places to Work in Dallas in 2024 &amp; 2025</li><li>100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 &amp; 2025</li></ul> <a href="https://builtin.com/awards/dallas/2025/best-midsize-places-to-work">Built In 2025 Award Lists</a><a href="https://www.greatplacetowork.com/certified-company/7049203">Great Place to Work Certification Page</a><a href="https://mostlovedworkplace.com/companies/colossal-biosciences/">Most Loved Workplace Certification Page</a> - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.<a href="https://www.newsweek.com/rankings/most-loved-workplaces-2024?utm_campaign=dr_2024_oct_webinar_final&amp;utm_medium=email&amp;_hsenc=p2ANqtz-8dglCEGpx_mr-HYudRKFhj4L6PhGDkf92pJJMpxovuNaX_Y7rdOFsgX6dEGZnNK9O_RP1gd54PPR7yib9CZjvG7FT4IA&amp;_hsmi=328042950&amp;utm_content=see_list&amp;utm_source=newlsetter">Newsweek's Most Loved Workplaces 2024 Award List</a> - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces! <img src="https://employers.builtin.com/wp-content/uploads/2023/09/2024BPTW_GeneralBadgeYear_AllWhite-1-281x300.png" style="max-width:100%;">   <img src="https://www.greatplacetowork.com/images/profiles/7049203/companyBadge.png?20240207" style="max-width:100%;">     <img src="https://pbs.twimg.com/media/FvJDPn0aEAAwgAH?format=jpg&amp;name=small" style="max-width:100%;">    <img src="https://colossal.com/wp-content/uploads/time-100.png" style="max-width:100%;"> <img src="https://imageio.forbes.com/dam/imageserve/65e730dcd08766cc9dbcdb47/x.jpg?format=jpg&amp;height=183&amp;width=255&amp;fit=bounds" style="max-width:100%;"> </div>

The science of genetics. The business of discovery.
Colossal is a breakthrough bioscience and genetic engineering company that builds radical new technologies to advance the field of genomics. Colossal creates disruptive technologies for extinct species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth. The company is the first to apply CRISPR technology for the purposes of species de-extinction, beginning with the woolly mammoth. Colossal is accepting humanity&rsquo;s duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition through cutting-edge science and technologies.

Research Associate, Molecular Biology

We are seeking a motivated and detail-oriented Research Associate to join our interdisciplinary team at the intersection of stem cell biology and genome engineering. This role offers the opportunity to work closely with scientists developing cutting-edge approaches to drive novel applications in the modification of phenotypes across a variety of avian species. The ideal candidate will bring strong technical skills in molecular biology, excellent problem-solving abilities, and a collaborative mindset to help drive innovation in species de-extinction and conservation.Duties and Responsibilities<ul><li>Collaborate with stem cell biologists to analyze gene expression profiles across different developmental stages and sample types using RT-qPCR.</li><li>Perform molecular cloning, construct design, and troubleshooting to support the genome engineering team.</li><li>Prepare and process samples for amplicon-based next-generation sequencing.</li><li>Analyze and interpret experimental data, providing recommendations to guide project direction.</li><li>Participate in lab meetings, generate reports, and present findings to ensure alignment with project milestones.</li><li>Maintain accurate, detailed laboratory records and demonstrate strong organizational skills.</li></ul>Required Skills and Abilities<ul><li>Bachelor’s degree (B.S./B.A.) in molecular biology, or a related life science field with 1 or more years of hands-on research experience in industry or academic research labs.</li><li>High proficiency in RNA extraction, reverse transcription, qPCR.&nbsp;</li><li>Skilled in PCR primer design and PCR optimization/troubleshooting.</li><li>Hands-on experience in molecular cloning, plasmid construction, and plasmid preparation (mini-, midi-, and maxi-prep).</li><li>Strong organizational skills with the ability to manage multiple projects simultaneously and meet deadlines.</li><li>Excellent written and oral communication skills, with demonstrated problem-solving abilities.</li></ul>Preferred Skills and Abilities<ul><li>Experience with genome-editing technologies (e.g., CRISPR/Cas9, HDR strategies).</li><li>Experience with multiplex RT-qPCR</li><li>Familiarity with high-throughput automation platforms for molecular biology workflows.</li></ul><div>What Colossal Offers You:<ul><li>Medical, dental, and vision coverage</li><li>Unlimited PTO and company holidays so you can rest and recharge&nbsp;</li><li>Flexible spending accounts (FSA)</li><li>Company matched 401k retirement plan</li><li>Paid parental leave up to 12 weeks</li><li>Education reimbursement&nbsp;</li><li>An opportunity to help us return the Earth to a healthier state</li></ul>The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.&nbsp;Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.&nbsp;<a href="https://www.eeoc.gov/after-june-27-2023-know-your-rights-workplace-discrimination-illegal">EEO is the Law&nbsp;</a>Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.&nbsp;Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:<ul><li>#1 on the 50 Best Startups to Work For in Dallas in 2023!</li><li>100 Best Midsize Places to Work in Dallas in 2024 &amp; 2025</li><li>100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 &amp; 2025</li></ul> <a href="https://builtin.com/awards/dallas/2025/best-midsize-places-to-work">Built In 2025 Award Lists</a><a href="https://www.greatplacetowork.com/certified-company/7049203">Great Place to Work Certification Page</a><a href="https://mostlovedworkplace.com/companies/colossal-biosciences/">Most Loved Workplace Certification Page</a> - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.<a href="https://www.newsweek.com/rankings/most-loved-workplaces-2024?utm_campaign=dr_2024_oct_webinar_final&amp;utm_medium=email&amp;_hsenc=p2ANqtz-8dglCEGpx_mr-HYudRKFhj4L6PhGDkf92pJJMpxovuNaX_Y7rdOFsgX6dEGZnNK9O_RP1gd54PPR7yib9CZjvG7FT4IA&amp;_hsmi=328042950&amp;utm_content=see_list&amp;utm_source=newlsetter">Newsweek's Most Loved Workplaces 2024 Award List</a> - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!&nbsp;<img src="https://employers.builtin.com/wp-content/uploads/2023/09/2024BPTW_GeneralBadgeYear_AllWhite-1-281x300.png">&nbsp; &nbsp;<img src="https://www.greatplacetowork.com/images/profiles/7049203/companyBadge.png?20240207">&nbsp; &nbsp; &nbsp;<img src="https://pbs.twimg.com/media/FvJDPn0aEAAwgAH?format=jpg&amp;name=small"> &nbsp; &nbsp;<img src="https://colossal.com/wp-content/uploads/time-100.png"> <img src="https://imageio.forbes.com/dam/imageserve/65e730dcd08766cc9dbcdb47/x.jpg?format=jpg&amp;height=183&amp;width=255&amp;fit=bounds">&nbsp;</div>

Research Associate, Molecular BiologyNew

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Colossal Biosciences

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