The Scientist will derive non-model organism primary cell lines, conduct assays corresponding to cell health, characterize lines, and occasionally perform microsurgeries. The candidate will be part of a core team responsible for optimizing and characterizing for lines derived in house and support other parts of the cell core team in gene editing workflows. This position reports to the Manger of Primary Cell and Production sub-team with the Cell Engineering and Production (CEP) core team. This position is based on-site in Dallas, TX. Relocation assistance is available.Duties and Responsibilities:<ul><li>Isolate, expand, and maintain high-quality primary cell cultures from diverse non-model animal tissues.</li><li>Innovate then execute experiments to generate and characterize primary cells from non-model mammalian organisms, develop functional assays, assess and interpret experimental workflows</li><li>Work with team members to coordinate and execute surgical procedures.</li><li>Work with team members to assess efficiency of workflows through cellular assays and NGS sequencing approaches</li><li>Work on project milestones</li><li>Attend lab meetings, prepare reports and presentations on the progress of projects</li><li>Great organizational skills and excellent laboratory record maintenance</li></ul>Required Schedule:<ul><li>Once onboarding is complete, this role will have a non-traditional workweek. The individual in this role will have 2 days off per week, but that may not be Saturday/Sunday. The individual must be available to work weekends. </li></ul>Required Skills and Abilities:<ul><li>Expert knowledge of primary cell derivation, culture, propagation, and biobanking</li><li>Expert knowledge and hands-on experience in CRISPR gene editing, including proficiency with multiple gene delivery methods such as chemical transfection, electroporation, and LNP delivery.</li><li>Experience with flow cytometry, immunostaining, confocal microscopy</li><li>Microdissection experience</li><li>Surgical experience</li><li>Strong Aseptic Technique and ability to work with antibiotic free culture</li><li>Strong written and oral communication skills, as well as creative problem-solving skills</li><li>Enjoys the fast-paced startup environment and teamwork</li><li>Exceptional organizational skills, multitasking, and attention to detail.</li><li>Strong emotional intelligence and passion for building relationships across all levels.</li><li>Ability to function well in a growth-oriented, nimble environment.</li></ul>Preferred Experience:<ul><li>Experience with automated cell culture workflows.</li><li>Previous work with mESC editing pipelines</li></ul>Education and Experience:<ul><li>PhD in biological sciences, stem cell biology, genetics or related field. BS/MS with significant relevant experience will also be considered</li><li>4+ years hands-on expertise in mammalian cell culture systems</li></ul><div>What Colossal Offers You:<ul><li style="font-weight:400;">Medical, dental, and vision coverage</li><li style="font-weight:400;">Unlimited PTO and company holidays so you can rest and recharge </li><li style="font-weight:400;">Flexible spending accounts (FSA)</li><li style="font-weight:400;">Company matched 401k retirement plan</li><li style="font-weight:400;">Paid parental leave up to 12 weeks</li><li style="font-weight:400;">Education reimbursement </li><li style="font-weight:400;">An opportunity to help us return the Earth to a healthier state</li></ul>The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices. Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive. <a href="https://www.eeoc.gov/after-june-27-2023-know-your-rights-workplace-discrimination-illegal">EEO is the Law </a>Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house. Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:<ul><li>#1 on the 50 Best Startups to Work For in Dallas in 2023!</li><li>100 Best Midsize Places to Work in Dallas in 2024 &amp; 2025</li><li>100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 &amp; 2025</li></ul> <a href="https://builtin.com/awards/dallas/2025/best-midsize-places-to-work">Built In 2025 Award Lists</a><a href="https://www.greatplacetowork.com/certified-company/7049203">Great Place to Work Certification Page</a><a href="https://mostlovedworkplace.com/companies/colossal-biosciences/">Most Loved Workplace Certification Page</a> - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.<a href="https://www.newsweek.com/rankings/most-loved-workplaces-2024?utm_campaign=dr_2024_oct_webinar_final&amp;utm_medium=email&amp;_hsenc=p2ANqtz-8dglCEGpx_mr-HYudRKFhj4L6PhGDkf92pJJMpxovuNaX_Y7rdOFsgX6dEGZnNK9O_RP1gd54PPR7yib9CZjvG7FT4IA&amp;_hsmi=328042950&amp;utm_content=see_list&amp;utm_source=newlsetter">Newsweek's Most Loved Workplaces 2024 Award List</a> - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces! <img src="https://employers.builtin.com/wp-content/uploads/2023/09/2024BPTW_GeneralBadgeYear_AllWhite-1-281x300.png" style="max-width:100%;">   <img src="https://www.greatplacetowork.com/images/profiles/7049203/companyBadge.png?20240207" style="max-width:100%;">     <img src="https://pbs.twimg.com/media/FvJDPn0aEAAwgAH?format=jpg&amp;name=small" style="max-width:100%;">    <img src="https://colossal.com/wp-content/uploads/time-100.png" style="max-width:100%;"> <img src="https://imageio.forbes.com/dam/imageserve/65e730dcd08766cc9dbcdb47/x.jpg?format=jpg&amp;height=183&amp;width=255&amp;fit=bounds" style="max-width:100%;"> </div>

The science of genetics. The business of discovery.
Colossal is a breakthrough bioscience and genetic engineering company that builds radical new technologies to advance the field of genomics. Colossal creates disruptive technologies for extinct species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth. The company is the first to apply CRISPR technology for the purposes of species de-extinction, beginning with the woolly mammoth. Colossal is accepting humanity&rsquo;s duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition through cutting-edge science and technologies.

Scientist, Cell Engineering

The Scientist will derive non-model organism primary cell lines, conduct assays corresponding to cell health, characterize lines, and occasionally perform microsurgeries. The candidate will be part of a core team responsible for optimizing and characterizing for lines derived in house and support other parts of the cell core team in gene editing workflows. This position reports to the Manger of Primary Cell and Production sub-team with the Cell Engineering and Production (CEP) core team.&nbsp;This position is based on-site in Dallas, TX. Relocation assistance is available.Duties and Responsibilities:<ul><li>Isolate, expand, and maintain high-quality primary cell cultures from diverse non-model animal tissues.</li><li>Innovate then execute experiments to generate and characterize primary cells from non-model mammalian organisms, develop functional assays, assess and interpret experimental workflows</li><li>Work with team members to coordinate and execute surgical procedures.</li><li>Work with team members to assess efficiency of workflows through cellular assays and NGS sequencing approaches</li><li>Work on project milestones</li><li>Attend lab meetings, prepare reports and presentations on the progress of projects</li><li>Great organizational skills and excellent laboratory record maintenance</li></ul>Required Schedule:<ul><li>Once onboarding is complete, this role will have a non-traditional workweek. The individual in this role will have 2 days off per week, but that may not be Saturday/Sunday. The individual must be available to work weekends.&nbsp;</li></ul>Required Skills and Abilities:<ul><li>Expert knowledge of primary cell derivation, culture, propagation, and biobanking</li><li>Expert knowledge and hands-on experience in CRISPR gene editing, including proficiency with multiple gene delivery methods such as chemical transfection, electroporation, and LNP delivery.</li><li>Experience with flow cytometry, immunostaining, confocal microscopy</li><li>Microdissection experience</li><li>Surgical experience</li><li>Strong Aseptic Technique and ability to work with antibiotic free culture</li><li>Strong written and oral communication skills, as well as creative problem-solving skills</li><li>Enjoys the fast-paced startup environment and teamwork</li><li>Exceptional organizational skills, multitasking, and attention to detail.</li><li>Strong emotional intelligence and passion for building relationships across all levels.</li><li>Ability to function well in a growth-oriented, nimble environment.</li></ul>Preferred Experience:<ul><li>Experience with automated cell culture workflows.</li><li>Previous work with mESC editing pipelines</li></ul>Education and Experience:<ul><li>PhD in biological sciences, stem cell biology, genetics or related field. BS/MS with significant relevant experience will also be considered</li><li>4+ years hands-on expertise in mammalian cell culture systems</li></ul><div>What Colossal Offers You:<ul><li>Medical, dental, and vision coverage</li><li>Unlimited PTO and company holidays so you can rest and recharge&nbsp;</li><li>Flexible spending accounts (FSA)</li><li>Company matched 401k retirement plan</li><li>Paid parental leave up to 12 weeks</li><li>Education reimbursement&nbsp;</li><li>An opportunity to help us return the Earth to a healthier state</li></ul>The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.&nbsp;Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.&nbsp;<a href="https://www.eeoc.gov/after-june-27-2023-know-your-rights-workplace-discrimination-illegal">EEO is the Law&nbsp;</a>Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.&nbsp;Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:<ul><li>#1 on the 50 Best Startups to Work For in Dallas in 2023!</li><li>100 Best Midsize Places to Work in Dallas in 2024 &amp; 2025</li><li>100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 &amp; 2025</li></ul> <a href="https://builtin.com/awards/dallas/2025/best-midsize-places-to-work">Built In 2025 Award Lists</a><a href="https://www.greatplacetowork.com/certified-company/7049203">Great Place to Work Certification Page</a><a href="https://mostlovedworkplace.com/companies/colossal-biosciences/">Most Loved Workplace Certification Page</a> - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.<a href="https://www.newsweek.com/rankings/most-loved-workplaces-2024?utm_campaign=dr_2024_oct_webinar_final&amp;utm_medium=email&amp;_hsenc=p2ANqtz-8dglCEGpx_mr-HYudRKFhj4L6PhGDkf92pJJMpxovuNaX_Y7rdOFsgX6dEGZnNK9O_RP1gd54PPR7yib9CZjvG7FT4IA&amp;_hsmi=328042950&amp;utm_content=see_list&amp;utm_source=newlsetter">Newsweek's Most Loved Workplaces 2024 Award List</a> - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!&nbsp;<img src="https://employers.builtin.com/wp-content/uploads/2023/09/2024BPTW_GeneralBadgeYear_AllWhite-1-281x300.png">&nbsp; &nbsp;<img src="https://www.greatplacetowork.com/images/profiles/7049203/companyBadge.png?20240207">&nbsp; &nbsp; &nbsp;<img src="https://pbs.twimg.com/media/FvJDPn0aEAAwgAH?format=jpg&amp;name=small"> &nbsp; &nbsp;<img src="https://colossal.com/wp-content/uploads/time-100.png"> <img src="https://imageio.forbes.com/dam/imageserve/65e730dcd08766cc9dbcdb47/x.jpg?format=jpg&amp;height=183&amp;width=255&amp;fit=bounds">&nbsp;</div>

Scientist, Cell Engineering

About the Job

About the Company

Colossal Biosciences

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